Search on: BLOCKING ANTIBODIES 
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Descriptor English:   Antibodies, Blocking 
Descriptor Spanish:   Anticuerpos Bloqueadores 
Descriptor Portuguese:   Anticorpos Bloqueadores 
Synonyms English:   Antibodies, Enhancing
Blocking Antibodies
Enhancing Antibodies  
Tree Number:   D12.776.124.486.485.114.143
D12.776.124.790.651.114.143
D12.776.377.715.548.114.143
Definition English:   Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989) 
Indexing Annotation English:   antibodies inhibiting reaction between antigen and other antibodies or sensitized T-lymphocytes: not for any antibody reaction to an antigen ( = ANTIBODIES or specific antibody); do not coordinate with ANTIBODY FORMATION for /biosyn
Pharmacological Action:   Immunologic Factors
 
History Note English:   96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PD pharmacology
PH physiology PO poisoning
RE radiation effects TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   32855 
Unique Identifier:   D019138 

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